The Institute of Sustainability, Health and Regional Engagement
(ISHARE) at the University of the Sunshine Coast has areas
of strength in Individual Physiological Health, and Biodiscovery to
Improve Human and Environmental Health. Research teams at USC are
active in developing new methods for monitoring biomarkers of cardio
vascular disease, and the discovery of novel antibiotics from Sunshine
Coast sources. Monitoring CVD biomarkers is benefitting from the ability
of high field NMR to quantify and characterize the biomarkers in untreated
serum and plasma. For example, NMR uses characteristic signals of
the lipoprotein subclasses as its bases for quantification and requires
no physical separation of the lipoproteins.
The biodiscovery team has isolated novel antibiotics active against
multi-drug resistant Staphylococcus aureus and Escherichia
coli. The structural elucidation relies most heavily on NMR data
and this work is in collaboration with groups at the IMB.
Other potential Sunshine Coast users of the Network via the USC hub
include the DPI, Nambour and regional hospitals.